Quality of life assessment after pancreatic enzyme replacement therapy in chronic pancreatitis: Statistical analysis
An attached module with 22 specific items included a disease-specific symptom scale (items 31 to 48), a treatment strain scale (items 49 to 51), and an overall hope and confidence scale (item 52). Because the QLQ-C30 questionnaire does not contain any question on steatorrhea, the original questionnaire was supplemented with two additional questions covering this symptom (items 47 and 48). Abdominal pain, as one of the leading symptoms of chronic pancreatitis, was also assessed (items 9, 19 and 41 to 46) (Figure 1) .
There are two choices in the scales for items 1 to 7, four choices for items 8 to 28 and 31 to 48, and seven choices for items 29, 30, 49 and 52. Items 50 and 51 allow narrative answers. For ease of interpretation, all scales and item scores were lineally transformed to a 0 to 100 scale. For the five functional scales and the overall QoL scale, a higher score reflects a better level of functioning. For the symptom-oriented scales, a higher score indicates a more severe level of symptoms.
Figure 1 (continued) Quality of life questionnaire
The parametric data are expressed as means ± SD. Nonparametric data are expressed as means and range. The paired Student’s t test was performed to evaluate the significance of differences between the pretreatment and follow-up body weight and defecation rate. The Wilcoxon rank test was used to estimate the significance of differences between pretreatment and follow-up QoL scores, and the Mann-Whitney U test test to evaluate the significance of differences between groups 1 and 2. Relationships between variables were characterized by the nonparametric Spearman rank correlation. P<0.05 was accepted as significant. Cheapest medications available at best pharmacy that you are free to try yourself! The best place to Buy Asthma Inhalers Online and be sure you are offered finest quality medications right from their actual manufacturers, which you do not get that often these days.