11 Aug

Quality of life assessment after pancreatic enzyme replacement therapy in chronic pancreatitis: RESULTS (Part 2)

A significant gain in body weight was found in both groups one month after the beginning of pancreatic enzyme replacement therapy, compared with the pretreatment values. The defecation rate was significantly reduced by 22% in group 1 and by 17 % in group 2 during follow-up. The prevalence of general and disease-specific symptoms was reduced in both groups after one month of enzyme substitution therapy. The pain score decreased by 24% in group 1 and by 22% in group 2 during follow-up.

The working ability, the financial strain and the overall QoL score were improved significantly in both groups, while the cognitive functioning score was significantly improved at follow-up only in group 1. The improvement in the physical status was statistically not significant in either group at the one-month follow-up. The overall QoL improved by 8.8% and 9.2% in groups 1 and 2, respectively. The overall increase in the QoL score correlated significantly with the increase in body weight and the decrease in defecation number in both groups (0.77 and 0.89 in group 1 [P<0.001] and 0.87 and 0.74 in group 2 [P<0.001], respectively). It’s your turn to benefit from the shopping whenever you need efficient Cheap Asthma Inhalers Online that will be sure to work for your problem. This is now all very much possible at the best online pharmacy you have ever come across offering it services to you and other international customers interested.

TABLE 3 Results of quality of life scores in group 2

Scales Items Pretreatment score Follow-up score Significance
Body weight (kg) 63.3±3.3 63.7±3.6 P=0.0047
Defecation/week 13.9±1.8 11.5±1.3 P=0.002
Physical status 1-5 83.1 84.1 P=0.776
Working ability 6,7 74.3 83.3 P=0.042
General symptoms 8-19 48.9 (5.5-88.8) 39.5 (0-83.3) P=0.000
Cognitive 20,25 77.5 78.2 (16.6-100) P=0.916
Emotional 21-24 48.5 56.2 (16.6-100) P=0.067
Social 26,27 68.7 * 71.2 P=0.223
Financial strain 28 45.0 * 63.3 P=0.000
Global quality of life 29,30 35.1 (0-66.6) 48.4 (16.6-83.3) P=0.013
Disease-specific symptoms 31-48 29.0 (0-76.4) 22.1 (0-56.9) P=0.002
Treatment strain 49 59.9 (16.6-100) 59.9 P=0.519
Hope and confidence 52 51.1 (16.6-100)* 47.8 (16.6-100)* P=0.429
Pain 9, 19, 38, 41-46 37.8 (9.5-85.7) 29.4 (0-85.7) P=0.008

© 2019 - Men’s Health Info Blog