Quality of life assessment after pancreatic enzyme replacement therapy in chronic pancreatitis: RESULTS (Part 2)
A significant gain in body weight was found in both groups one month after the beginning of pancreatic enzyme replacement therapy, compared with the pretreatment values. The defecation rate was significantly reduced by 22% in group 1 and by 17 % in group 2 during follow-up. The prevalence of general and disease-specific symptoms was reduced in both groups after one month of enzyme substitution therapy. The pain score decreased by 24% in group 1 and by 22% in group 2 during follow-up.
The working ability, the financial strain and the overall QoL score were improved significantly in both groups, while the cognitive functioning score was significantly improved at follow-up only in group 1. The improvement in the physical status was statistically not significant in either group at the one-month follow-up. The overall QoL improved by 8.8% and 9.2% in groups 1 and 2, respectively. The overall increase in the QoL score correlated significantly with the increase in body weight and the decrease in defecation number in both groups (0.77 and 0.89 in group 1 [P<0.001] and 0.87 and 0.74 in group 2 [P<0.001], respectively). It’s your turn to benefit from the shopping whenever you need efficient Cheap Asthma Inhalers Online that will be sure to work for your problem. This is now all very much possible at the best online pharmacy you have ever come across offering it services to you and other international customers interested.
TABLE 3 Results of quality of life scores in group 2
|Scales||Items||Pretreatment score||Follow-up score||Significance|
|Body weight (kg)||63.3±3.3||63.7±3.6||P=0.0047|
|General symptoms||8-19||48.9 (5.5-88.8)||39.5 (0-83.3)||P=0.000|
|Financial strain||28||45.0 *||63.3||P=0.000|
|Global quality of life||29,30||35.1 (0-66.6)||48.4 (16.6-83.3)||P=0.013|
|Disease-specific symptoms||31-48||29.0 (0-76.4)||22.1 (0-56.9)||P=0.002|
|Treatment strain||49||59.9 (16.6-100)||59.9||P=0.519|
|Hope and confidence||52||51.1 (16.6-100)*||47.8 (16.6-100)*||P=0.429|
|Pain||9, 19, 38, 41-46||37.8 (9.5-85.7)||29.4 (0-85.7)||P=0.008|