06 Aug

Quality of life assessment after pancreatic enzyme replacement therapy in chronic pancreatitis: Patients inclusion criterion

pancreatic enzyme replacement therapy

Whereas the alleviation of steatorrhea and pain during pancreatic enzyme replacement therapy in chronic pancreatitis has been demonstrated , the effect of this treatment on QoL is not known. By employing the modified QLQ-C30 questionnaire in this prospective, multicentre, follow-up study, we have evaluated the QoL in patients with chronic pancreatitis who underwent pancreatic enzyme replacement therapy.

A prospective, multicentre, follow-up study was performed. The inclusion criterion, a diagnosis of chronic pancreatitis, was based on morphological and functional tests. Establishment of the morphological diagnosis of chronic pancreatitis included the use of abdominal ultrasonography, computed tomography, magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography. The patients were divided into a mild or a severe exocrine insufficiency group, depending on the results of the pancreatic function tests and the degree of steatorrhea.

The exocrine pancreatic function was assessed by performing the Lundh test (mild – fewer than six abnormal parameters; severe -more than six abnormal parameters) , the lipiodol test (normal – greater than 2.8 mEq/24h) , estimation of the fecal elas-tase (normal – greater than 200 pg/g; mild – less than 200 pg/g; severe – less than 100 pg/g feces) and chymotrypsin (normal – greater than 20 U/g; mild – less than 20 U/g; severe -less than 6 U/g feces) concentrations. Looking for a great online pharmacy you could trust and where you could find generic sildenafil online at best prices? You have one pharmacy like that already and can finally enjoy the best quality of service ever experienced.

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