04 Aug

Quality of life assessment after pancreatic enzyme replacement therapy in chronic pancreatitis (Part 1)

pathophysiology of chronic pancreatitis

The pathophysiology of chronic pancreatitis is puzzling, the classification of the disease is unsatisfactory and no standardized treatment is available . The application of new treatment modalities without controlled interdisciplinary studies intensifies the problem. Earlier studies on the natural course of chronic pancreatitis and the effects of different treatment modalities have focused on the morbidity and mortality of the disease, the onset of an exocrine and an endocrine insufficiency, and the severity of pain .

Pain is the leading symptom of chronic pancreatitis, but it reflects only one aspect of the multidimensionality of the quality of life (QoL). In a benign disease such as chronic pancreatitis, the ultimate aim of any treatment modality must be an improvement of the patient’s QoL. Assessment of the QoL is currently receiving increasing attention as a standard evaluation criterion for treatment options targeting patients with chronic pancreatitis.

QoL assessment was first applied for evaluation of the outcome in cancer treatment . The European Organization for the Research and Treatment of Cancer (EORTC) demonstrated that the Quality of Life Questionnaire Core 30 (QLQ-C30) QoL measurement system is a practical, reliable, valid and cross-culturally applicable method. A pharmacy you can fully trust is ready to offer best selection of cheap and effective medications that work the way they are expected to every time and are always available: you could buy generic levitra professional and enjoy all the convenient services offered right now.

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