19 Apr

Plexiform neurofibroma of the submandibular salivary gland in a child

Plexiform neurofibromaNeurofibromatosis type 1 is an autosomal dominant inherited neurocutaneous syndrome with an incidence of one per 3000 births. A mutation on chromosome 17 is responsible for Von Recklinghousen’s disease. The clinical diagnosis is based on the criteria as outlined by the National Institutes of Health consensus conference. Patients present with multiple lesions, including cafe-au-lait spots, osseous lesions, Lisch nodules, gliomas and neurofibromas. Your drugs could be so cheap – get asthma inhalers at trusted foreign online pharmacy.

Plexiform neurofibromas are nonmetastasizing, locally aggressive, invasive tumours that cause cosmetic and functional deformities in the head and neck region. They are rarely located in major salivary glands, but when present are most commonly located in the parotid gland region and seldom located in the submandibular region.

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