23 Sep

Persistent upper gastrointestinal symptoms despite proton pump inhibitor therapy: Psychometric validity (Part 1)

The term ‘stomach problems’ for question 1 was considered adequate by 65% (13 of 20) of the English- and 67% (eight of 12) of the French-speaking patients to describe their symptoms.

Demographics and baseline characteristics

Overall, 158 English-speaking patients (mean age 56 years, 41% male) and 113 French-speaking patients (mean age 58 years, 31% male) participated in this phase of the study. The educational backgrounds for the English-speaking group were college or university (36%), high school (47%) and elementary school (17%); the corresponding figures for the French-speaking group were 31%, 53% and 16%, respectively.

At baseline, all patients had GOS scores of at least 3 (of 7 possible), with a median GOS score of 4 for both the English-and French-speaking groups. There were no significant differences in demographics between the English and French patient groups. All patients were receiving PPI therapy at baseline: omeprazole (37%), pantoprazole (31%), lansoprazole (16%) and rabeprazole (16%). Two hundred forty-nine patients of the initial 271 remained in the study for four weeks after visit 2 and completed the follow-up assessments. Except for two patients (with a compliance rate of less than 80%), all patients had a high compliance rate with the medication during the four-week treatment phase. Get most advantageous deals ever – generic sildenafil online click here waiting for you round the clock.

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