Patients with Chronic Paralytic/Restrictive Ventilatory Dysfunction: Results (1)
The 18 BV-assisted patients with a mean Sa02 of ^95 percent had a mean of 2.4 ±3.1 4%dSaC>2/h. The 19 BV-assisted patients with a mean Sa02 of <95 percent had a mean of 22.3 ± 15.5 4%dSa(Vh, including 13 with a mean of more than ten 4%dSaO<j/h (Table 1). Five of the 18 patients with a mean Sa02 of ^95 percent for the entire night had, nonetheless, a mean Sa02 of <95 percent for at least 1 h, with an average mean of six 4%dSa02 episodes per hour during sleep. antibiotic levaquin
Fourteen of the 15 patients with respiratory symptoms despite use of a BV had a mean Sa02 of <95 percent during nocturnal monitoring. Eleven of the 15 had more than ten 4%dSa02 episodes per hour. Only three symptomatic patients and two other patients (patients 6, 7, 10, 22, and 33) with a mean Sa02 of <95 percent had fewer than ten 4%dSa02 episodes per hour. These five patients with more prolonged dSa02 episodes and fewer dSa02 episodes with rapid recovery had a pattern more consistent with chronic underventilation than with obstructive episodes. They used chest shells, which along with the rocking bed, are the two least effective BVs. Four of the five patients used less than 12 h of ventilatory aid per day and were underventilated when not using an aid. Patients 6 and 7 had the longest recorded periods of continuous dSa02 <90 percent (318 and 43 min, respectively) and Sa02 <85 percent (56 and 18 min, respectively).