09 Sep

Management of polycystic liver disease

Polycystic liver diseasePolycystic liver disease (PCLD) is a rare condition that is frequently associated with polycystic kidney disease (PCKD) but may also occur independently. The prevalence of PCLD is approximately 0.15% in the general population, with the majority going undetected . However, multiple simple hepatic cysts are common in the general population at 2% to 10%, and may be confused with PCLD. Most cases of PCLD are associated with the autosomal dominant PCKD, which has an incidence of one in 800. In these patients, up to 55% will develop PCLD . Isolated PCLD occurs in less than 20% of cases and is a condition independent of PCKD . In both forms of PCLD, more severe cystic involvement has been associated with increasing age and more severe renal dysfunction . In addition, sex and hormonal factors play an important role, with more extensive lesions in females and patients with a history of multiple pregnancies. Interestingly, massive hepatic cyst disease occurs almost exclusively in females . With ongoing advancements in dialysis and the medical management of PCKD, patients surviving longer will be at increased risk of developing symptoms and complications from PCLD progression. Management of PCLD will become an important issue in these patients, whose morbidity was previously limited to cystic kidney disease. You will always find levitra professional sale checkout now, shopping online with pleasure every time.

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