29 Aug

Erythema nodosum and pyoderma gangrenosum: RESULTS Patient group

Figure 1 shows the entire population of 1015 Crohn’s disease patients evaluated directly by the clinician investigator for more than two decades. As shown for each age group, there was a predominantly female pattern. In the database, there were a total of 50 patients (4.9%) with erythema nodosum and/or pyoderma gangrenosum. This included 45 patients with erythema nodosum (4.4%) and seven patients with pyoderma gangrenosum (0.7%). Two patients had both dermatological disorders (0.2%). Although not further evaluated here, metastatic cutaneous Crohn’s disease with granulomas was recorded in one woman from this population with erythema nodosum.

These values for erythema nodosum and pyoderma gangrenosum approximate percentages reported from a similar large study that used a coded database over a 10-year period of evaluation, rather than direct clinician evaluation here for a similar mean period of patient follow-up over 10 years . In this patient group, 41 of 566 women (7.2%) and nine of 449 men (2.0%) were affected with either erythema nodosum or pyoderma gangrenosum. The results from this prospectively accumulated database approximate the reported frequencies for these dermatological disorders detailed elsewhere in retrospective surveys and a single prospective study.
In this population, recurrent erythema nodosum was also detected in nine patients (20%; eight women and one man, P<0.05), while recurrent pyoderma gangrenosum was seen in two patients (28.6%; one woman and one man). You can always be sure whenever you buy ventolin inhalers it is going to be one enjoyable and great experience overall, since you can now choose yourself a perfect pharmacy that will give you best quality medications with no prescription required.

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