Archive for the 'Upper gastrointestinal symptoms' Category - Part 2

17 Sep

Persistent upper gastrointestinal symptoms despite proton pump inhibitor therapy (Part 4)

The GOS is a seven-point Likert scale, scored from 1 (no problem) to 7 (very severe problem), that measures the overall severity of dyspepsia symptoms. The GSRS includes 15 questions that address GI symptoms in five different domains: reflux, abdominal pain, indigestion, diarrhea and constipation. The GSRS questions are answered using a seven-point Likert-like scale, […]

16 Sep

Persistent upper gastrointestinal symptoms despite proton pump inhibitor therapy (Part 3)

Laboratory measurements, including a urine pregnancy test if applicable, were performed at the second visit. All patients then received open label treatment with esomeprazole 40 mg taken each morning, 30 min before breakfast, for the next four weeks. Esomeprazole was chosen because of its superiority, at standard dose, to other PPIs at increasing gastric pH […]

15 Sep

Persistent upper gastrointestinal symptoms despite proton pump inhibitor therapy (Part 2)

A history and physical examination were performed in all patients and baseline demographic data were recorded. Adverse events and the use of concomitant medications were recorded throughout the study. PPI use during the week before entry into the study was documented. Patients then completed the PASS test and the Global Overall Symptom (GOS) scale to […]

14 Sep

Persistent upper gastrointestinal symptoms despite proton pump inhibitor therapy (Part 1)

The PASS (Proton pump inhibitor Acid Suppression Symptom) test format was finalized based on an analysis of the content validity questionnaire results (Figure 1). Psychometric validation of the PASS test was performed in a three-visit multicentre study at 38 family practice centres across Canada to evaluate ‘test-retest’ reliability, construct validity and responsiveness. The study protocol […]

© 2019 - Men’s Health Info Blog