Archive for the 'Pulmonary Hypertension' Category

25 Jun

Assessment of Left Ventricular Diastolic Function After Single Lung Transplantation in Patients With Severe Pulmonary Hypertension: Conclusion

In this study, Doppler echocardiography was utilized to determine left ventricular filling dynamics. There are a number of variables affecting transmitral Doppler parameters, such as age, heart rate, mitral regurgitation, and loading conditions. Age is unlikely to have significant impact on our results. Our patient age was relatively young (average, 32 years). As seen in […]

23 Jun

Assessment of Left Ventricular Diastolic Function After Single Lung Transplantation in Patients With Severe Pulmonary Hypertension: Discussion

Our results agree with their findings regarding abnormal left ventricular filling; however, in our patients, the deformation of left ventricular geometry was seen throughout systole and diastole. Severe tricuspid regurgitation in our patients (eight of nine) may account for the difference. Regarding the mechanism of the left ventricular filling abnormalities in this setting, Louie et […]

21 Jun

Assessment of Left Ventricular Diastolic Function After Single Lung Transplantation in Patients With Severe Pulmonary Hypertension: Late Changes After Lung Transplantation

Late Changes After Lung Transplantation One year later, the improvement in both right ventricular function and left ventricular geometry was sustained in all surviving patients. One patient died from respiratory failure 4 months after transplantation. A significant reduction in left ventricular relaxation time (from 127±14 to 91 ±8, p<0.05) was observed 1 year later after […]

19 Jun

Assessment of Left Ventricular Diastolic Function After Single Lung Transplantation in Patients With Severe Pulmonary Hypertension: Results

Clinical and Doppler Echocardiographic Features In the patient group, there were eight female patients and one male patient with mean age of 32 years (range, 15 to 48 years). Six patients were diagnosed as having primary pulmonary hypertension and the other three were diagnosed as having secondary pulmonary hypertension due to ventricular septal defect, atrial […]

17 Jun

Assessment of Left Ventricular Diastolic Function After Single Lung Transplantation in Patients With Severe Pulmonary Hypertension: Materials and Methods

Left ventricular isovolumic relaxation time was measured as a time interval from aortic closure click to the beginning of the mitral inflow in the apical five-chamber view with a continuous wave cursor positioned to straddle the left ventricular inflow and outflow tract. A sweep speed of 100 cm/s was used for this recording. A standardized […]

15 Jun

Assessment of Left Ventricular Diastolic Function After Single Lung Transplantation in Patients With Severe Pulmonary Hypertension

Right ventricular pressure overload causes the deformation of the left ventricle by septal flattening toward its cavity, which may result in impaired left ventricular early filling. Recent studies have demonstrated the ability of single lung transplantation to restore right ventricular function in patients with severe pulmonary hypertension. However, changes in left ventricular filling after single […]

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