Archive for the 'Exhaled Ethane' Category

22 Aug

Effect of Vitamin E on Exhaled Ethane in Cigarette Smokers: Conclusion

This would be in keeping with the study by Britton et al in which the effect of vitamin C alone was greater than vitamin E. It may be that both vitamin C and vitamin E and possibly P-carotene are needed for effective antioxidant activity in that redox cycling occurs within these agents. Second, despite our […]

20 Aug

Effect of Vitamin E on Exhaled Ethane in Cigarette Smokers: Outcome

Thus, a wide variability in micronutrient levels would be expected, and the resultant effects on ethane production would be variable as well. However, once antioxidant levels are raised by supplementation such that they are high and the antioxidant effects are at their maximum, variations in ethane would be the result of oxidant effect rather than […]

18 Aug

Effect of Vitamin E on Exhaled Ethane in Cigarette Smokers: Micronutrient antioxidants

Cigarette smokers have been shown to have lower levels of micronutrient antioxidants through poor intake, increased metabolism, or their oxidation as they perform their purported duties of reducing antioxidant stress. In the current study, we found no correlation between β-carotene levels on entry into the study and measures of lung function (data not shown). Also, […]

16 Aug

Effect of Vitamin E on Exhaled Ethane in Cigarette Smokers: Discussion

Measurement of exhaled alkanes has been used by us and others as a noninvasive marker of lipid peroxidation. We favor ethane over pentane as a measure of lipid peroxidation because of the more rapid metabolism of pentane by animals and man. In addition, mass spectroscopic analysis of human exhalate demonstrates the presence of significant amounts […]

14 Aug

Effect of Vitamin E on Exhaled Ethane in Cigarette Smokers: Lung function

Exhaled ethane was negatively associated with FEV1/FVC in general (Fig 3), but this negative correlation achieved statistical significance only after vitamin E intake (Fig 3, center, B). The negative association between exhaled ethane and FEV1 percent predicted was also observed at all time points but never achieved statistical significance. The relationship between lung function and […]

12 Aug

Effect of Vitamin E on Exhaled Ethane in Cigarette Smokers: Results

The demographic profiles of the subjects recruited for this study appear in Table 1. Most subjects were male (86%), reflecting the largely male population of patients at the Veterans Affairs Medical Center. They ranged in age from 42 to 75 years with the mean (± SD) being 59.5 (± 10.4) years. These subjects smoked a […]

10 Aug

Effect of Vitamin E on Exhaled Ethane in Cigarette Smokers: Venous blood

Immediately after the ethane was collected and while the cassettes were still very cold, the charcoal from each trap was poured into a 13.27-mL test tube that was quickly sealed with an open screw top housing a 13-mm TFE/silicone septum (Alltech; Deerfield, IL). The two test tubes were heated for 3 min at 250°C and […]

08 Aug

Effect of Vitamin E on Exhaled Ethane in Cigarette Smokers: Exhaled breath

Compliance with taking the vitamin was confirmed by pill count and blood levels. Each subject was studied on four occasions, 3 weeks apart. On each visit, exhaled breath ethane was measured and samples of serum were taken for measurement of vitamin E and ^-carotene. Between visits 1 and 2, subjects were asked to refrain from […]

06 Aug

Effect of Vitamin E on Exhaled Ethane in Cigarette Smokers: Materials and Methods

In that previous study, the ability of the micronutrient antioxidants to reduce exhaled ethane was correlated closely with their lung function as measured by percent predicted FEV1. The better preserved the FEV1 in these smokers, the greater was the reduction in exhaled ethane after supplementation. We hypothesized that even when antioxidants are administered, they may only […]

04 Aug

Effect of Vitamin E on Exhaled Ethane in Cigarette Smokers

Although cigarette smoking is the most important factor in the development of COPD, the mechanisms by which cigarette smoke leads to obstructive airways disease is not fully understood. Approximately 15 to 20% of cigarette smokers develop clinically significant COPD. Understanding the mechanisms of smoking-induced injury may allow us to predict which smokers will progress to develop […]

© 2017 - Men’s Health Info Blog