Archive for the 'Advanced colon cancer' Category

08 Sep

Advanced colon cancer before the age of 20 years: DISCUSSION (Part 2)

It has clearly been established that screening is necessary because of the history of rapid adenoma to carcinoma progression in patients manifesting HNPCC. In one 15 year trial, colonoscopic screening at three-year intervals more than halves the risk of colorectal cancer, prevents deaths due to colorectal cancer, and decreases overall mortality by approximately 65% in […]

07 Sep

Advanced colon cancer before the age of 20 years: DISCUSSION (Part 1)

At laparotomy there was an obvious large tumour of the cecum extending halfway up the ascending colon and involving the terminal ileum and urinary bladder. There was mild evidence of ascites but there was no surface peritoneal tumour growth, nor were there any palpable liver metastases. He subsequently underwent a right hemicolectomy and partial cystectomy. […]

06 Sep

Advanced colon cancer before the age of 20 years: CASE PRESENTATION

A flexible sigmoidoscopy performed 20 days after his emergency department presentation was unremarkable and he had not had a second episode of rectal bleeding in the intervening time period. His previous symptoms had resolved completely. The only remarkable feature about this patient was that his mother had undergone a right hemicolectomy 12 years previously at […]

05 Sep

Advanced colon cancer before the age of 20 years

Hereditary nonpolyposis colorectal cancer (HNPCC) currently accounts for 2% to 6% of all colorectal adenocarcinomas. The HNPCC syndrome has classically been divided into two subgroups based on clinical presentation: Lynch I, which has no history of associated cancers, and Lynch II, which can present along with other malignancies, including cancer of the stomach, uterus, urinary […]

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